GoDubai
  
  
  
  
Citylife > Press Release
  Home Contact us Add to Favourites
Most Recent Postings
More Press Releses
Featured Sections

Event Finder
A daily roundup of exhibitions, promotions and other events in Dubai and the rest of the Emirates.
Submit an Event
Latest Dubai Press Releases >>

 
  Share

13 February 2018, Dubai, UAE:   This International Childhood Cancer Day, paediatric haematologist expert, Professor Ajay Vora, from Great Ormond Street Hospital in London (GOSH) discusses how advances in cellular therapy are set to revolutionise treatment for children with acute lymphoblastic leukaemia (ALL). 

Acute lymphoblastic leukaemia (also called ALL or acute lymphocytic leukaemia) is a cancer of the blood and bone marrow.  Leukaemia is one of the ten most common malignancies in Saudi Arabia, Kuwait and UAE, and a major form of paediatric cancer. In the UAE, a recent study found a high rate of ALL (32%) among males. 

According to Professor Vora, childhood leukaemia outcomes have improved in the past four decades, with 90% of children with ALL surviving. These improvements in outcomes have also translated for children in the Middle East as well. 

“There are a number of new pioneering treatments being developed at GOSH to treat leukaemia using immune cells, and some of these are being tested in clinical trials”, explains Prof. Vora. “These treatments are experimental and are only considered when routine chemotherapy treatments haven't worked. A Kuwaiti patient will soon be the first international patient to receive CAR-T cell therapy at GOSH.”

CAR-T cell therapy, a type of cellular therapy currently being trialled at GOSH to treat ALL, involves collecting a patient's own white blood cells (or immune cells) and modifying them so they can attack specific cancers.

“One major issue, especially in infants, is the difficulty in collecting enough of the right type of immune cells (T cells)”, Prof. Vora explains. “For such cases, new approaches are being tested that use T cells from a healthy donor but are modified using ‘gene-editing' so they don't need to be matched to the patient. This means the cells are ‘universal' and can be produced in advance and stored frozen, ready to be used in multiple patients.” 

The gene-edited T cells (called UCART19) are given to patients immediately after a course of chemotherapy and antibody therapy. They are expected to circulate around the body and fight any leukaemia carrying the CD19 marker. Responses are assessed after one month, and if remission had been achieved, the patient will proceed to have a bone marrow transplant. At that stage the cells are removed and do not persist long-term.

This innovative treatment is currently available at GOSH as part of its research trials, and will become available in the near future to patients from across the world once the research phase is over. 

“Cellular therapy has the potential to revolutionise the treatment of leukaemia in children. Currently, it provides a chance to treat patients who have failed to respond to other treatment. If further research confirms preliminary data on efficacy, in future, it will provide a less toxic alternative to haemopoietic stem cell transplantation,” Prof. Vora concludes.

GOSH, who treats 1,500 children from the Middle East every year, has treated 271 haematology patients between April – Dec 2017.

 



Posted by : GoDubai Editorial Team
Viewed 8754 times
Posted on : Tuesday, February 13, 2018  
Replication or redistribution in whole or in part is expressly prohibited without the prior written consent of GoDubai.com.
Previous Story : Arianna Huffington calls for a Third Women's Revolution to redesign a world focused on Augmented Hum...
Next Story : WGS 2018: Mindfulness Is an Awareness of the Here and Now, Emphasizes Stress Management Expert
Email this article Print this article

Share this article with your friends and followers
NewsVine

Comments

Back to Top  
Most Viewed Press Release posted in the last 7 days
Bhima Jewellers inaugurates new store in Rolla, Sharjah
Mouawad Acquires The 51.38 Carat Dynasty Diamond From ALROSA
Panasonic's latest LUMIX DMC-TZ220 is the Ultimate Travel Companion
Summer Spirit
Instantly Refreshed Hair with HASK
Joyalukkas brings joy to hundreds around the world with summer gold bar giveaway
How to choose the right mascara
Kaya Skin Clinic's Expertise is pushing the Boundaries of Botox
Tissot Chrono XL NBA Team Collection Sporty Gets Smart
Build Your Perfect Skincare Routine with Essentials from Glambeaute.com
Hour Choice presents Coach Astor Collection
Joyalukkas adds a new destination for jewellery lovers in Al-Balad, Jeddah, KSA
Taresh Al Hashimi's Oud Concert Brings Stories from the UAE's Coast to Brazil
Creating #futureclassic: Swatch Launches Skin Irony Collection
Transform your look with the ‘Perfect Brows'
FALL 2018
Delicious Whole Cakes at Sophie's Café from AED99
13 Emirati Authors Launched into the Portuguese Book Market
Dual Front Camera and Artificial Intelligence Power the Next Generation Super Selfies
Head to Modhesh World for Summer Fun Before the School Run
Ferrari introduces the world's first low-bake paint technology
“The world is thirsty for an Arab superhero"
Huawei Consumer Business Group Announces 2018 H1 Business Results
Favourite florals: Bloom with our top floral picks from bebe
Scuderia Ferrari presents ASPIRE collection
Business Wear by Hugo Boss
This Eid gift your someone special from the Hour Choice Eid Special collections.
Introducing the GUESS Jeans Fall 2018 Collection
Never Run Out of Space for Those Joyful Summer Holiday Memories With Western Digital
The Marriott International cyclist team completes 600km R2A cycle challenge
Carl F. Bucherer Presents Adamavi Collection
Carl F. Bucherer's Global Brand Ambassador Li Bingbing and Her Carl F. Bucherer ...
This Eid gift your someone special from the Hour Choice Eid Special collections
Joyalukkas opens newest showroom in Kuwait at Farwaniya
The Rado HyperChrome Ultra Light
Calligraphy, etching and Palestinian embroidery: Learn it all at Tashkeel this S...
Cerruti 1881 MOLVENO timepiece and cufflinks
‘The Little Things' That Makes Summer All The More Enjoyable
Garment Grooming at its Finest with Champion Cleaners
Dubai Land Department supports strategic alliance between the UAE and China
Sharjah Takes ‘Year of Zayed' Celebrations beyond Borders
MEFMA reaffirms commitment to promote entrepreneurship & innovation across local...
The 2nd Edition of the Phanes Group Solar Incubator set to kick off 7th August 2018
Danube Properties' Dh550 million Lawnz project at International City, sold out i...
Big Android Breakthrough: Huawei's power packed GPU Turbo upgrade will turn you...
Emirates Intellectual Property Association leads unified efforts to promote adop...
The Sharjah Chamber of Commerce and Industry discusses cooperation with Malaysia
du LaLiga HPC Top Talents Arrive in Spain for 21-day Annual Scouting Camp
Hilton Launches New Platform Dedicated to Offering Guests Bespoke, Unforgettable...
Celebrate India's Independence Day with Sparkles of India