GoDubai
  
  
  
  
Citylife > Press Release
  Home Contact us Add to Favourites
Most Recent Postings
More Press Releses
Featured Sections

Event Finder
A daily roundup of exhibitions, promotions and other events in Dubai and the rest of the Emirates.
Submit an Event
Latest Dubai Press Releases >>

 
  Share

13 February 2018, Dubai, UAE:   This International Childhood Cancer Day, paediatric haematologist expert, Professor Ajay Vora, from Great Ormond Street Hospital in London (GOSH) discusses how advances in cellular therapy are set to revolutionise treatment for children with acute lymphoblastic leukaemia (ALL). 

Acute lymphoblastic leukaemia (also called ALL or acute lymphocytic leukaemia) is a cancer of the blood and bone marrow.  Leukaemia is one of the ten most common malignancies in Saudi Arabia, Kuwait and UAE, and a major form of paediatric cancer. In the UAE, a recent study found a high rate of ALL (32%) among males. 

According to Professor Vora, childhood leukaemia outcomes have improved in the past four decades, with 90% of children with ALL surviving. These improvements in outcomes have also translated for children in the Middle East as well. 

“There are a number of new pioneering treatments being developed at GOSH to treat leukaemia using immune cells, and some of these are being tested in clinical trials”, explains Prof. Vora. “These treatments are experimental and are only considered when routine chemotherapy treatments haven't worked. A Kuwaiti patient will soon be the first international patient to receive CAR-T cell therapy at GOSH.”

CAR-T cell therapy, a type of cellular therapy currently being trialled at GOSH to treat ALL, involves collecting a patient's own white blood cells (or immune cells) and modifying them so they can attack specific cancers.

“One major issue, especially in infants, is the difficulty in collecting enough of the right type of immune cells (T cells)”, Prof. Vora explains. “For such cases, new approaches are being tested that use T cells from a healthy donor but are modified using ‘gene-editing' so they don't need to be matched to the patient. This means the cells are ‘universal' and can be produced in advance and stored frozen, ready to be used in multiple patients.” 

The gene-edited T cells (called UCART19) are given to patients immediately after a course of chemotherapy and antibody therapy. They are expected to circulate around the body and fight any leukaemia carrying the CD19 marker. Responses are assessed after one month, and if remission had been achieved, the patient will proceed to have a bone marrow transplant. At that stage the cells are removed and do not persist long-term.

This innovative treatment is currently available at GOSH as part of its research trials, and will become available in the near future to patients from across the world once the research phase is over. 

“Cellular therapy has the potential to revolutionise the treatment of leukaemia in children. Currently, it provides a chance to treat patients who have failed to respond to other treatment. If further research confirms preliminary data on efficacy, in future, it will provide a less toxic alternative to haemopoietic stem cell transplantation,” Prof. Vora concludes.

GOSH, who treats 1,500 children from the Middle East every year, has treated 271 haematology patients between April – Dec 2017.

 



Posted by : GoDubai Editorial Team
Viewed 9723 times
Posted on : Tuesday, February 13, 2018  
Replication or redistribution in whole or in part is expressly prohibited without the prior written consent of GoDubai.com.
Previous Story : Arianna Huffington calls for a Third Women's Revolution to redesign a world focused on Augmented Hum...
Next Story : WGS 2018: Mindfulness Is an Awareness of the Here and Now, Emphasizes Stress Management Expert
Email this article Print this article

Share this article with your friends and followers
NewsVine

Comments

Back to Top  
Most Viewed Press Release posted in the last 7 days
Brow Contour Pro 4-in-1 defining & highlighting brow pencil
Jessica Kahawaty in Dubai to Celebrate the Launch of SUKIN, Australia's No.1 Nat...
BodyO launches officially its AiPod for a full body check-up during the Gitex Fu...
The World of Aigner Wunderkammer
Get flawless skin with Rodial's new Booster Drops
Johnson's launches Fresh Hydration Range – Cleansed, hydrated skin in just #OneSwipe
Manero Peripheral (43 Mm) Classic Watchmaking Meets State of,the Art Technology
Curate your perfect Autumn Winter wardrobe, with Robinsons
Fifi & Friends - Now available at more outlets across the UAE
Corum Heritage Eleganza- Dedicated to the stylish woman
Halloween “Catwoman” mask using BROW products
BOLLYWOOD PARKS™ Dubai introduces 11 new shows with a new line up of performance...
Dubai Shopping Festival Returns With Much-awaited Mega Raffles
With more collections and a more spacious car parking, Kalyan Silks moves to El...
Win up to 250,000 Gold coins at Malabar Gold & Diamonds this festive season
Joyalukkas Celebrates the Festival of Light with Irresistible Offers
OMEGA gets set to time the Youth Olympic Games Buenos Aires 2018
Malabar Gold & Diamonds to triple number of outlets to 750 and raise Group turno...
Dubai's newest social hub - Bar Baar introduces ‘Thela Baar Brunch'
Sharjah Government pavilion highlights digital transformation of Sharjah at GITE...
Hour Choice presents Coach Park Collection (Suede straps)
Introducing the Nokia 7.1 to the UAE
Saddle Up With kate spade Fall 2018
Michael Kors to Introduce a Special-edition Whitney Handbag for the Middle East
W Motors and Safe City Group introduce the BEAST PATROL at GITEX: One of the mo...
Be Thankful with Tub of Butter This Thanksgiving
CITIZEN Unveils 100th Anniversary Limited Edition Collection
Rado DiaMaster Ceramos Automatic
Scuderia Ferrari Aspire Watch Special Edition Gift Set
The Ford F-150 Raptor: Your Ultimate Partner for Off-Road Adventure
Sharjah Girl Guides Unleash their Power on International Day of the Girl Child
Toyota's legendary King goes urban with the 2019 Land Cruiser Grand Touring Edition
Nissan to Make Official On-track Formula E Debut
Western Digital powers AI-enabled storage for futuristic surveillance and security
Sunglasses Trends for Fall/Winter 2018
SIBF 2018 Invites Young Visitors to the Wondrous Land of Edutainment
Provacuno - Spain's largest Inter-professional Association introduces Spanish Be...
UAE Toastmasters community to host the world champion of public speaking
Healthcare leaders sign in Dubai a Call for Action to raise awareness about ‘sil...
Daikin eyes significant expansion of business in the UAE
Delizioso! The Week of the Italian Cuisine in the World Returns to the UAE
Dubai's Jehad Medical Clinic bags JCI for the third time
Synx, Pand.ai, and AIMLedge named winners of startAD's Artificial Intelligence V...
HUGO BOSS Watches Jump Collection
Dubai Business Women Council witnesses 36.5% growth in total membership since th...
Dubai Festival City Run 2018 to take place on November 9th
Epson Introduces the New A3 and A4 business inkjet aimed at busy workgroups duri...
Ministry of Human Resources and Emiratization (MOHRE) Honors Union Coop for its ...
Tissot Bella Ora Round Style incarnate
Avivo's Ribbon of Life Walk in support of Breast Cancer on 19th October